Antibody discovery with Salipro®

Antibody discovery with Salipro®

One of the main hurdles to the development of novel therapeutic antibodies against GPCRs and ion channels is directly coupled to the transmembrane topology of these drug targets, making them difficult to extract and purify from the lipid bilayer of the cell without disrupting their native conformation.

The Salipro® technology reconstitutes challenging targets while preserving the native structure and function of these drug targets in stable, lipid-containing nanoparticles.

Drug targets stabilized in Salipro® nanoparticles can be utilized in a wide array of downstream applications within antibody discovery and characterization.