New study in Cell uses Salipro technology for investigating autoimmune disease
Salipro® technology enables the determination of underlying mechanisms of autoimmune encephalitis. In a new study published in Cell, researchers identified anti-neuronal antibodies bound to the GABAA receptor by combining Salipro technology with cryoEM.
Congratulations to Noviello and the team for the identification of autoantibodies in complex with the Salipro-GABAA receptor!
Publication reference:
C. M. Noviello, et al., Structural mechanisms of GABAA receptor autoimmune encephalitis. Cell 185, 2469-2477 (2022).